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    Researchers found that participants investing in this drug for any year, lost weight within one month and have kept the extra weight off during the entire 56 weeks with the study. Contrave is really a combination with the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which can be made up of several active ingredient, which might make them more potent and safer.

    Combo-pilling will be the newest fad or also the newest ahead under scrutiny and therefore it is just more publicly known recently, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills is becoming popular will be the fact that by right now there are no long term prescription weight loss supplements that have been licensed by the FDA other than orlistat. The truly disturbing part is doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be approved by the FDA.

    Seizures can be a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug also can raise blood pressure and heart rate, and mustn't be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy using the drug.

    The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not be used in patients with uncontrolled high blood pressure levels, as well as by anyone with heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients having a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients on the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stopping smoking.

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